AFA or Aphanizomenon flos-aquae, (a blue green alga growing naturally in Klamath Lake in Southern Oregon) has been used as a dietary supplement for more than two decades. Most commonly reported benefits are a reduction of the symptoms of inflammatory conditions such as rheumatism, arthritis, as well as asthma. Recently, phycocyanin, the active ingredient has been isolated. Aphanin is an extract from AFA that contains the highest concentration of phycocyanin.